Abstract:In-situ leaching uranium mining is a kind of in-situ ore mining method through the dissolution reaction between leaching solution and uranium bearing minerals in sandstone layer. It is of great significance to improve the efficiency of in-situ uranium mining to clarify the three-dimensional structure of ore bed and aquifer overlying it. On the basis of data collection, combined with well logging data, geostatistics method was used to fine classify the strata and ore layers in the mining area, the corresponding three-dimensional geological model was established, and the spatial structure characteristics of ore-bearing aquifer was analyzed according to the model simulation results. The analysis results show that the main lithology of ore-bearing aquifer is coarse sandstone. The ore-bearing aquifer has good pore connectivity and uniform distribution of permeable lithology. The formation dip of the mining area is approximately 325° and the dip angle is 6.76°. The thickness of the top water-repellent layer is thicker in the south and middle part, and thinner in the north and west part. Seven water-repellent roof skylights are developed. The thickness of the ore bed is close to the water-repellent floor, and gradually drops from the north to all directions. The thickness of the ore bed is positively correlated with the thickness of ore-bearing aquifer. The construction of three-dimensional geological structure model completely and intuitively shows the three-dimensional spatial distribution characteristics of strata and rock mass in C12 mining area of Bayanwula uranium mine, which can provide scientific basis for further numerical simulation research of in-situ leaching uranium mining.